LungCancer Panel

Catalog Number:

#1001922 (16 rxn)
#1001921 (96 rxn)

LungCancer Panel v1.0 is specifically designed for lung cancer research. This panel involves 24 genes, including full coding regions from 19 genes and non-exonic regions with frequent fusion occurrence in lung cancer.

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Gene List

Genes with coding regions covered

*ALK*	*BRAF*	*CD274*	CD74	*EGFR*	*ERBB2*	EZR	*FGFR1*	*FGFR2*	*FGFR3*	*KRAS*	*MET*
*NRAS*	*NTRK1*	*NTRK2*	*NTRK3*	NUTM1	*PDCD1LG2*	*PDGFRA*	*PIK3CA*	*RET*	*ROS1*	SDC4	SLC34A2

Genes with full coding regions shown in bold.

Performance

Table 1. Performance of LungCancer Panel v1.0

Platform

On-target rate (%)

Duplication (%)

% target

> 0.2 x mean

% target

> 0.5 x mean

% target

> 1 x mean

Fold 80 base penalty

MGI

92.75

6.20

99.21

96.21

52.12

1.28

Illumina^®️

93.98

12.21

99.98

97.92

52.14

1.27

The DNA libraries were prepared from human genomic DNA (Promega, G1521). 1 M read pairs were subsampled for the analysis.

Fig 1. Evaluation of LungCancer Panel v1.0 on the analysis of SNVs and indels. The DNA libraries were prepared from Onco SNV Multiplex 1-25% gDNA (GeneWell, GW-OGTM004) using NadPrep library kits. The enriched libraries were sequenced either on HiSeq X Ten (PE150) or DNBSEQ-G400 (PE100).

For research use only. Not for use in diagnostic procedures.

Catalog#	Color Of Tube Cap	Item	Volume	Package/Storage
1001922		LungCancer Panel v1.0, 16 rxn	70 μl×1	–20℃
1001921		LungCancer Panel v1.0, 96 rxn	415 μl×1	–20℃